• Users Online: 161
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current Articles Search Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2019  |  Volume : 1  |  Issue : 1  |  Page : 12-19

Multimodal Monitoring Technologies for Pathophysiology and Management of Traumatic Brain Injury


1 Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China
2 Department of Neurosurgery, Southwest Hospital, Third Military Medical University; College of Biomedical Engineering, Third Military Medical University, Chongqing, China
3 Department of Neurosurgery, Chongqing Municipal Emergency Medical Center, Chongqing, China

Correspondence Address:
Dr. Hua Feng
Department of Neurosurgery, Southwest Hospital, Third Military Medical University, 29 Gaotanyan Street, Shapingba District, Chongqing 400038
China
Login to access the Email id


DOI: 10.4103/jtccm.jtccm_2_18

Get Permissions

Despite decades of efforts, severe traumatic brain injury (TBI) is still the leading cause for mortality and immobility of children and young adults worldwide and is a great burden to the health-care system. After injury, the oxygen supply is conventionally considered the monitoring parameter in a neurosurgical Intensive Care Unit. However, the overall mortality rate has only slightly improved since the late twentieth century. Evolving evidence suggests that dysfunction of oxygen utilization might be the underlying pathophysiology of secondary brain injury, which should also be a key parameter for multimodal monitoring and management after severe TBI. In this review, we summarize the current and advanced understanding of multimodal monitoring for severe TBI along with novel noninvasive technologies in this field. By continuously monitoring patients with severe TBI, the use of multimodal monitoring technologies including (but not limited to) computed tomography, cerebral microdialysis, near-infrared spectroscopy, magnetic resonance spectroscopy, high-performance liquid chromatography, and magnetic induction phase shift method will be crucial for observing disease changes such as intracranial pressure and brain tissue oxygen partial pressure as well as developing potential therapeutic strategies after severe TBI.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3022    
    Printed264    
    Emailed0    
    PDF Downloaded425    
    Comments [Add]    

Recommend this journal