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Year : 2022  |  Volume : 4  |  Issue : 1  |  Page : 13

Endotoxemic Sepsis: Clinical Features and Therapy

1 Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Spectral Medical, Toronto, Ontario, Canada
2 Toray Medical Co., Ltd., Tokyo, Japan
3 Spectral Medical, Toronto, Ontario, Canada

Correspondence Address:
Dr. John A Kellum
Spectral Medical Inc., 135 The West Mall, Unit 2, Toronto, Ontario M9C 1C2

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JTCCM-D-22-00015

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Heterogeneity in clinical presentation for patients with sepsis complicates treatment and prognosis and limits the development of new therapy. Reasons for this heterogeneity is unclear but recent studies have identified sub-types sepsis defined by clinical features. These sub-types may be brought about by certain triggers such as endotoxin and may further require a susceptible host. Treatment with hemoperfusion to remove endotoxin is discussed.

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