PERSPECTIVE |
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Year : 2022 | Volume
: 4
| Issue : 1 | Page : 13 |
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Endotoxemic Sepsis: Clinical Features and Therapy
John A Kellum1, Hisataka Shoji2, Debra Foster3, Paul M Walker3
1 Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Spectral Medical, Toronto, Ontario, Canada 2 Toray Medical Co., Ltd., Tokyo, Japan 3 Spectral Medical, Toronto, Ontario, Canada
Correspondence Address:
Dr. John A Kellum Spectral Medical Inc., 135 The West Mall, Unit 2, Toronto, Ontario M9C 1C2
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/JTCCM-D-22-00015
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Heterogeneity in clinical presentation for patients with sepsis complicates treatment and prognosis and limits the development of new therapy. Reasons for this heterogeneity is unclear but recent studies have identified sub-types sepsis defined by clinical features. These sub-types may be brought about by certain triggers such as endotoxin and may further require a susceptible host. Treatment with hemoperfusion to remove endotoxin is discussed.
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