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REVIEW ARTICLE
Year : 2022  |  Volume : 4  |  Issue : 1  |  Page : 5

Diaphragm-Protective Mechanical Ventilation: Saving the Diaphragm from the Detrimental Effects of Mechanical Ventilation


1 Department of Intensive Care Medicine, Amsterdam University Medical Centers; Amsterdam Cardiovascular Sciences Research Institute, Amsterdam University Medical Centers, Amsterdam, Netherlands; Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
2 Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
3 Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands

Correspondence Address:
Prof. Leo Heunks
Erasmus Medical Center, Postbus 2040, 3015 GD, Rotterdam
The Netherlands
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JTCCM-D-21-00017

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Diaphragm weakness develops in up to 80% of the critically ill patients, and is associated with adverse clinical outcomes. Mechanical ventilation has been proposed to play a role in the development of diaphragm weakness in critically ill patients, especially by ventilator under-assist or ventilator over-assist. Therefore, in addition to the concept of lung-protective ventilation to protect the lung, diaphragm-protective ventilation has been recently proposed to limit the development of diaphragm weakness. In this concise review, we will discuss the current evidence for diaphragm-protective ventilation and the clinical consequences.


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