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REVIEW ARTICLE
Year : 2022  |  Volume : 4  |  Issue : 1  |  Page : 9

Pain and its Management in Severe Acute Pancreatitis


Department of Critical Care Medicine, Chongqing University Cancer Hospital, Chongqing, China

Correspondence Address:
Dr. Zhengying Jiang
Department of Critical Care Medicine, Chongqing University Cancer Hospital, Chongqing 400030
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JTCCM-D-21-00026

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Pain is common in severe acute pancreatitis (SAP) and is associated with the disease severity and outcomes. The management of pain in SAP may not only relieve pain but also improve outcomes. However, pancreatic pain in SAP involves several complicated mechanisms. Poor understanding about the pain mechanism in SAP and lack of enough high-quality data on pharmacological and nonpharmacological intervention lead to a limited analgesia strategy in patients with SAP mainly managed using nonsteroidal anti-inflammatory drugs and opioids. This makes pain management in SAP challenging and may cause potential harm. This article reviewed the current management of pain in SAP by combining pain mechanisms with animal or clinical studies and proposed an analgesic ladder based on available evidence to improve pain management in patients with SAP.


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